Karen Parks Studio Recital

Kennesaw State University School of Music presents Karen Parks Studio Recital.https://digitalcommons.kennesaw.edu/musicprograms/1764/thumbnail.jp

Final Design Report: Allergen Mixing Assistant (AMA) Micro-Refrigeration Redesigning

Abstract Allergen Mixing Assistant (AMA) by Xtract Solutions is a device designed to more “effectively refrigerate, organize, and mix allergenic extracts”. Although Xtract Solutions intended the product to be fully automated, the company has decided against its automation and declared its current design as a minimum viable product whose components are too expensive, difficult to source and complex. Therefore, Cal Poly AMA design team - Mitchell Parks and Minwoo Suh - has decided to replace these expensive components with much more economical alternatives as shown below: Stirling cooler → Thermoelectric (Peltier) cooler Custom Arduino Controller Card → TEC Thermostat *** Original Housing with Wasted Space * → New Housing ** The cost analysis of the new design quotes the Allergen Mixing Assistant at $730, albeit minus the labor cost and manufacturing time, much more economical than the previous design where the Stirling Cooler alone was quoted at$830. Beyond its cost-effectiveness, the new Allergen Mixing Assistant has been improved from its previous design in following categories: 1, more effective cooling; and 2, better packaging - its overall physical dimensions have been reduced. Testing proved that a larger focus on heat rejection is needed to maintain the desired set temperature. Due to insufficient heat dissipation our new unit is unable to run for extended periods of time, but will be a viable option if a larger heat sink can be obtained

Tendinosis develops from age- and oxygen tension-dependent modulation of Rac1 activity.

Age-related tendon degeneration (tendinosis) is characterized by a phenotypic change in which tenocytes display characteristics of fibrochondrocytes and mineralized fibrochondrocytes. As tendon degeneration has been noted in vivo in areas of decreased tendon vascularity, we hypothesized that hypoxia is responsible for the development of the tendinosis phenotype, and that these effects are more pronounced in aged tenocytes. Hypoxic (1% O2 ) culture of aged, tendinotic, and young human tenocytes resulted in a mineralized fibrochondrocyte phenotype in aged tenocytes, and a fibrochondrocyte phenotype in young and tendinotic tenocytes. Investigation of the molecular mechanism responsible for this phenotype change revealed that the fibrochondrocyte phenotype in aged tenocytes occurs with decreased Rac1 activity in response to hypoxia. In young hypoxic tenocytes, however, the fibrochondrocyte phenotype occurs with concomitant decreased Rac1 activity coupled with increased RhoA activity. Using pharmacologic and adenoviral manipulation, we confirmed that these hypoxic effects on the tenocyte phenotype are linked directly to the activity of RhoA/Rac1 GTPase in in vitro human cell culture and tendon explants. These results demonstrate that hypoxia drives tenocyte phenotypic changes, and provide a molecular insight into the development of human tendinosis that occurs with aging

Peridigm users' guide. V1.0.0.

Abstract Not Provide

Probing upper thermospheric neutral densities at Mars using electron reflectometry

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95666/1/grl20594.pd

Geographies of landscape: Representation, power and meaning

Green criminology has sought to blur the nature-culture binary and this article seeks to extend recent work by geographers writing on landscape to further our understanding of the shifting contours of the divide. The article begins by setting out these different approaches, before addressing how dynamics of surveillance and conquest are embedded in landscape photography. It then describes how the ways we visualize the Earth were reconfigured with the emergence of photography in the 19th century and how the world itself has been transformed into a target in our global media culture